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Oral Rehydration Salts (ORS)

Gastrointestinal

WHO-formula glucose-electrolyte solution for diarrheal dehydration.

Generic name: Sodium chloride / Potassium chloride / Sodium citrate / Glucose
Brand names: Oresol, Hydrite, Oralyte

Dosage

Dissolve one sachet in the exact volume of clean water printed on the packet. Give frequent small sips. Adults can drink ad libitum; children 50–100 mL per loose stool, infants 10 mL/kg per loose stool.

Side effects

Very rare. Slight nausea if drunk too fast. Risk of hypernatremia only with under-dilution.

Contraindications

Intestinal obstruction, severe ongoing vomiting (use IV fluids), anuria.

Description

Reduced-osmolarity ORS (245 mOsm/L) is the WHO standard since 2002 and the first-line therapy for any-cause diarrheal dehydration. Co-transport of glucose and sodium across the intestinal mucosa drives rapid water absorption even when secretory diarrhea is ongoing.

Reference information only; not medical advice.